Fig. 7
Drug tolerant cells exhibit altered cell state. a Immunoblots for neuronal differentiation and stem markers in sensitive and drug-tolerant D458 cells in the presence of JQ1 (1 μM) or DMSO control. Source data: Source Data File. b Percentage of BrdU positive D425 and D458 sensitive and drug-tolerant cells following 72 h of treatment with JQ1 (1 μM) or DMSO control. Data represent three independent experiments per cell line; error bars depict mean ± SEM. Asterisks denote significant differences (*p < 0.05, **p < 0.01, ***p < 0.001) as determined by two-tailed unpaired t-tests. Source data: Source Data File
