Fig. 7
From: A toll-like receptor agonist mimicking microbial signal to generate tumor-suppressive macrophages
Assessment of the safety of acGM-1.8 in vivo. a acGM-1.8, or four classical TLR ligands: LPS, MPLA, Poly (I:C) and Pam3CSK4, was intraperitoneally injected to mice at the same dose. The survival rate was calculated after 24 h of injection; n = 10. b Measurement of the key biochemical parameters, including creatine kinase (CK), lactic dehydrogenase (LDH), blood urea nitrogen (BUN), and alanine transaminase (ALT), in the serum of the mice alive after injected with PBS, Pam3CSK4, or acGM-1.8 (20 mg/Kg); *P < 0.05 versus the PBS treatment; n = 5
