Table 1 List of AlzForum disease-associated mutations

From: Tau local structure shields an amyloid-forming motif and controls aggregation propensity

Name

Amino-acid sequence

Tau RD AlzForum Mutations a

R1: 244 QTAPVPMPDLKN-V K SK I GSTEN L KHQP GG GK 274

R2: 275 VQII N KKLD LS N-VQSKCGSKD N IKH VP G G G S 305

R3: 306 VQIVYKPVDLSK-VTSKCGSLGNIHHKPGGGQ 336

R4: 337 V EVKSE K LDFKDRVQ S KIG S LDN I TH VP G G GN 368

  1. aSites of mutation are shown in bold