Fig. 1
From: CHML promotes liver cancer metastasis by facilitating Rab14 recycle
CHML is upregulated in HCC and predicts poor survival. a Real-time PCR analysis of CHML mRNA in 45 paired HCC tumor tissues and normal tissues. b Box plots comparing levels of CHML mRNA in normal human liver tissues and hepatocellular carcinoma tissues in published data sets from oncomine. ***P < 0.001, Student’s t-test. c Western blot analysis of CHML expression in 24 paired normal (N) and HCC tumor (T) tissues. GAPDH is used as internal control. Arrow demonstrates the CHML band, and NS means non-specific band. d Immunohistochemistry staining of CHML in 3 paired normal liver and HCC tumor. Scale bar, 50 μm. e Kaplan–Meier analysis of overall survival of tissue microarray (TMA) data containing 297 patients. f Kaplan–Meier analysis of overall survival data from TCGA liver cancer data containing 364 patients. g, h Kaplan–Meier analysis of recurrence-free survival of the TMA data (g) and TCGA-LIHC data (h). All data are represented as mean ± s.e.m.
