Fig. 1 | Nature Communications

Fig. 1

From: A synthesis strategy for tetracyclic terpenoids leads to agonists of ERβ

Fig. 1

Tetracyclic terpenoid skeletons and a means of synthesis from epichlorohydrin. a The general skeleton of tetracyclic terpenoids (C18 through C20). b A unified enantiospecific route to a variety of tetracyclic terpenoid motifs. c Application to the synthesis of a euphane-based tetracyclic skeleton and the synthesis and discovery of a potent and selective agonist of the estrogen receptor beta (ERβ)

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