Fig. 4 | Nature Communications

Fig. 4

From: Efficient base editing for multiple genes and loci in pigs using base editors

Fig. 4

Base editing pigs were generated by SCNT. a Summary of SCNT results for generation of DMD mutant and RAG1, RAG2, and IL2RG mutant cloned pigs. b Image of DMD heterozygous female pigs produced in this study. c Genotype of DMD heterozygous female piglets. d Representative images of five cloned piglets with C-to-T conversions in RAG1, RAG2, and IL2RG genes. e Sanger sequencing chromatograms of DNA from wild-type and five cloned piglets. The red arrow indicates the substituted nucleotides

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