Table 1 CaMKK2 expression by molecular breast cancer subtypes

From: CaMKK2 in myeloid cells is a key regulator of the immune-suppressive microenvironment in breast cancer

 

Viennaa

RPCIb

Combinedc

CaMKK2

N

LA

LB

TN

N

LA

LB

TN

N

LA

LB

TN

Low

32

75%

9%

16%

54

65%

19%

16%

86

69%

15%

16%

High

15

40%

20%

40%

14

43%

7%

50%

29

41%

14%

45%

ORd

 

0.2

nd

ns

 

ns

nd

5.0

 

0.3

nd

4.1

p-valuee

 

0.0241

nd

ns

 

ns

nd

0.0129

 

0.0107

nd

0.0026

  1. N  sample numbers, nd  not determined, ns  not significant
  2. Immunohistochemical analysis of CaMKK2 expression in human breast cancer tissue microarrays, from two independent datasets (8 and Roswell Park Cancer Institute, RPCI). CaMKK2 expression was determined to be low (<2) or high (> = 2), and correlated with molecular subtypes: triple negative (TN), luminal A (LA), and luminal B (LB). Fisher’s exact test was used to determine p-values for the likelihood of association
  3. aVienna data set; 47 samples
  4. bRoswell Park Cancer Institute data set; 68 samples
  5. cVienna and RPCI combined
  6. d,eOdds ratio and associated p-value
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