Table 2 Multiple linear regression of explanatory variables to atherosclerotic lesion area within the aortic sinus of FCG mice

From: XX sex chromosome complement promotes atherosclerosis in mice

 

Estimate

Standard Error

t-value

P-value

(Intercept)

13.23

0.49

26.8

<0.0000000000000002

Body weight (g)

0.01

0.02

0.56

0.58

Sera cholesterol (mg/dl)

−0.00

0.00

−1.43

0.16

Gonadal fat (%)

0.08

0.09

0.88

0.38

Genetic background:

    

Ldlr−/− mice

−0.07

0.36

−0.19

0.85 < 0.0000000000000002

C57BL/6 mice

−4.62

0.23

−19.95

0.85 < 0.0000000000000002

Sex

−0.09

0.17

−0.56

0.58

Surgery (Intact)

0.01

0.27

0.03

0.98

Sex chromosome genotype

−0.99

0.21

−4.77

0.000011

  1. Reference groups were Apoe−/− mice (genetic background), female (sex), GDX (surgery), and XX genotype (sex chromosome genotype)