Fig. 2
From: In situ structure and assembly of the multidrug efflux pump AcrAB-TolC
In situ Cryo-ET structures of the fully assembled AcrAB–TolC complex. a The side-view projection of the subtomogram average of the pump in presence of antibiotics. b Isosurface rendering of a fitted with high resolution cryo-EM model (PDB: 5V5S). c A slice through b showing a constriction at the boundary between AcrA and TolC (indicated by the red arrow). d A slice through the density map of the pump in presence of AcrB inhibitor (MBX3132). e Isosurface rendering of b overlaid with density map of the cell envelope
