Fig. 2
The benchmarking study to validate the PIN algorithm. a The uncropped SDS-PAGE gel showing the effect of sample treatment with different amounts of protease on the proteome level. Lanes: 1, MW Marker; 2, Controls (without protease treatment); 3–8, Samples F-A as defined in Table 1. b Scatter plot of sorted PIN values of the samples of the benchmarking study. The samples with P-values above 0.05 are marked in blue; those with P-values between 0.001 and 0.05 are in coffee; those with P-values between 1e−5 and 0.001 are in orange; those with P-values below 1e−5 are in dark red
