Table 1 The overall experimental design and results of the benchmarking study

From: Comparative analysis of mRNA and protein degradation in prostate tissues indicates high stability of proteins

Sample

# biological replicates

# technical replicates

Proteinase K concentration (μg/μl)

PIN

P-value

A

2

2

0.0200

0.645

3.17E-17

B

2

2

0.0100

0.714

2.07E-13

C

2

2

0.0040

0.850

2.73E-06

D

2

2

0.0020

0.868

2.15E-05

E

2

2

0.0010

0.900

9.87E-04

F

2

2

0.0005

0.933

0.039

Control

18

2

N.A.

0.964

0.721

  1. P-values were obtained from the PIN algorithm by probability distribution fitting
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