Fig. 3
From: Inhibition of CRISPR-Cas9 ribonucleoprotein complex assembly by anti-CRISPR AcrIIC2
AcrIIC2Nme functions as a homodimer. a The crystal structure of AcrIIC2Nme solved by Se-SAD reveals a dimeric protein containing both α-helical and β-strand structural elements. Monomers are colored in violet and deep salmon, and the N- and C-termini are noted. b Cartoon representation of AcrIIC2-Nme1Cas9 complex. c Surface representation of AcrIIC2-Nme1Cas9 complex. d Electrostatic surface potential of AcrIIC2-Nme1Cas9 complex. e, f Interactions between the bridge helix and AcrIIC2Nme. The bridge helix is shown in cyan. AcrIIC2.1 and AcrIIC2.2 are shown in violet and deep salmon, respectively
