Fig. 5
From: Sustainable and recyclable super engineering thermoplastic from biorenewable monomer
In vitro and in vivo biocompatibility tests. a In vitro cytotoxicity tests using pristine media (negative control) and those containing 5% DMSO (positive control) or polymer film extracts, following ISO 10993-5. Each value represents the mean and standard deviation of quintuplicate samples. b In vivo experiment procedure: rat subcutaneous connective tissues (n = 5) with HDPE (negative control), SUPERBIO, and BPA-SEP films. c Representative histopathologic tissue images after 12 weeks of healing. Arrows for inflammatory cells: red (polymorphonuclear cell), black (lymphocyte), and blue (macrophage)
