Fig. 2
Recurrently altered genes in ATC and advanced DTCs. The frequencies of recurrent gene alterations among diverse types of TC were represented by radar charts. a TERT, b TSGs, c TP53, and d the frequencies of AKT1/PIK3CA and EIF1AX co-mutations with BRAFV600E or RAS in diverse types of TC (blue). The mutational frequencies without BRAFV600E and RAS were also displayed (orange). e The distribution of recurrent oncogene mutations across 113 TCs. f The functional domains of PDE8B–TERT fusion. g The expression level of TERT at each exon with PDE8B-TERT fusion. h The expression level of TERT by alteration type. P-values from DESeq2 were represented. i A schematic illustration of TERT upstream translocation. The breakpoints were pointed out by arrows
