Fig. 4
From: Decoupling of timescales reveals sparse convergent CPG network in the adult spinal cord
Two timescales of synaptic input. a Sample data of recordings of two spinal neurons kept hyperpolarized to prevent spiking during network activity (onset indicated, pair from Fig. 3c). Highlighted region indicates concurrent membrane potentials. b Separating traces into slow (top) and fast signals (bottom) by digital filtering. c Common synaptic input is quantified by the correlation of the fast signal in a temporal window (400 ms) moving in time, i.e. correlogram with time on x-–axis, time–lag on y-–axis. A small albeit significant correlation is seen as a yellow horizontal shadow. d The zero–lag correlation (blue) indicates no clear temporal relation to the rhythm. Distribution shown vertically (right, μ= 0.29). Shuffled data (beige). e Strong slow correlation (0.99), whereas the fast is weak (0.36, excluding quiescence), indicating a decoupling between slow rate modulation and fast synaptic input. f Paired recording from same cell as control. g Correlogram for same–cell dual recordings similar to c. h Same–cell recording show coupling between slow and fast correlation (both peak at 1)
