Fig. 2
From: Genomic signatures reveal DNA damage response deficiency in colorectal cancer brain metastases
Mutational spectrum of DDR genes in brain metastases and matched primary tumors of CRC patients. Mutations occurring only in BM tissues are presented in red, and mutations occurring only in primary tissues are presented in blue; shared mutations are presented in grey. Genes involved in homologous recombination and nonhomologous end joining are marked in red. Bold rectangle indicates that the mutations appear in the founding clones
