Fig. 8
From: PRKCSH contributes to tumorigenesis by selective boosting of IRE1 signaling pathway
PRKCSH enhances expression of tumor-promoting cytokines under ER stress. a Quantitative real-time PCR analysis of tumor-promoting cytokines in L02-Mock and L02-PRK cells treated with 10 μg/mL TM for 5 h. b Quantitative real-time PCR analysis of tumor-promoting cytokines in PRKCSH-silenced Huh-7 cells treated with 10 μg/mL TM for 5 h. c Quantitative real-time PCR analysis of tumor-promoting cytokines in PRKCSH-silenced HepG2 cells treated with 10 μg/mL TM for 5 h. d Quantitative real-time PCR analysis of tumor-promoting cytokines in IRE1α-silenced L02-PRK cells treated with 10 μg/mL TM for 5 h. Data are shown as mean ± SEM from three or four independent experiments. One-way ANOVA; *P < 0.05, **P < 0.01
