Fig. 10 | Nature Communications

Fig. 10

From: Sensory cortex wiring requires preselection of short- and long-range projection neurons through an Egr-Foxg1-COUP-TFI network

Fig. 10

Proposed model for short- and long-range projection neuron selection. After the cell cycle exit, Egr2 is activated in early postmitotic neurons and suppresses Foxg1 expression in the lower intermediate zone. This downregulation of Foxg1 derepresses COUP-TFI in postmitotic neurons and confers short-range projection neuron identity. VZ/SVZ ventricular zone/subventricular zone, IZ intermediate zone, CP cortical plate

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