Fig. 6 | Nature Communications

Fig. 6

From: circTP63 functions as a ceRNA to promote lung squamous cell carcinoma progression by upregulating FOXM1

Fig. 6

CENPA and CENPB are regulated by cicrTP63 through FOXM1. a The mRNA and protein levels of cell cycle-related genes in H226 and H2170 cells with circTP63 overexpression. b Expression changes of CENPA, CENPB, and CCNB1 after knockdown of FOXM1 in H2170 cells with circTP63 overexpression. c Cell proliferation assay for H226 and H2170 cells with circTP63 overexpression and joint knockdown of CENPA and CENPB. d Hypothesis diagram illustrates function and mechanism of circTP63 in LUSC progress. The error bars a–c represent s.d. (n = 3). *p < 0.05; **p < 0.01; ***p < 0.001, two-tailed t-test. Source data are provided as a Source Data file

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