Fig. 1 | Nature Communications

Fig. 1

From: A murine neonatal model of necrotizing enterocolitis caused by anemia and red blood cell transfusions

Fig. 1

Neonatal murine model of red blood cell (RBC) transfusion-associated necrotizing enterocolitis (NEC)-like injury. a Schematic shows the sequence of interventions in naive control, transfusion control, anemic control, and anemic-transfused mice. b Longitudinal change in hematocrit in mice subjected to repeated phlebotomy. Line diagrams (means ± standard error, SE) show serial hematocrits in control vs. anemic mice. c Hematocrit in the four study groups. Scatter column plots (means ± SE) show the hematocrit values on P12 (24 h after transfusions). Data in b, c represent N = 42 animals in naive control, 21 in transfusion control, 18 in anemic control, and 21 in anemic-transfused groups. Kruskal–Wallis H test with Dunn’s post test, *P < 0.05, †P < 0.001 vs. naive control

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