Fig. 7

A model for the functional role of UBR7 in N-mediated resistance to TMV. a In uninfected naive condition, UBR7 interacts with the TIR domain of N resulting in the relatively low expression of N. b During TMV infection, the p50 effector disrupts the interaction between UBR7 and N by interacting with UBR7, thereby releasing the N from the N-UBR7 complex and leading to increased stability of N and activation of defense