Fig. 4 | Nature Communications

Fig. 4

From: Evidence against tetrapod-wide digit identities and for a limited frame shift in bird wings

Fig. 4

D1 has a unique, conserved gene expression profile across amniotes. a Venn diagrams of one-to-one orthologous transcription factors genes of mouse, alligator, and chicken that are differentially expressed between adjacent digits (FDR threshold of 0.05). b Heatmap showing relative expression of genes in D2 and D1. Human transcriptomic data provides additional support for the hypothesis that D1 has a conserved developmental identity across amniotes. c Expression levels of T-box family genes across the autopod. Transcript per million (TPM) values presented in panels b and c calculated from the gene list of one-to-one orthologous genes between mouse, alligator, Anolis, chicken, and human. Source data for panels b and c are provided as a Source Data file

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