Fig. 3
From: Antimalarial activity of primaquine operates via a two-step biochemical relay

Dose-response viability of late stage gametocytes treated with PQ and OH-PQm upon reaction with human CPR. Compounds at concentrations ranging from 30 μM to 11.7 nM were incubated with human CPR and diluted 1:3 for GC-LUC assays (n = 2, each in triplicate). IC50s (±S.E.M.) were calculated from nonlinear regression (curve fit) in GraphPad Prism