Fig. 4 | Nature Communications

Fig. 4

From: FDA-ARGOS is a database with public quality-controlled reference genomes for diagnostic use and regulatory science

Fig. 4

Comparison of NCBI Nt and FDA-ARGOS read classification results. Visualizing bioinformatics analysis with the MegaBLAST tool of metagenomics shotgun data of mock clinical human blood sample spiked with 105 E. avium. The heatmap showed read classification results for triplicate samples run against 200 database instances. Dark blue indicates read numbers below 10. A gradient from white to red indicates read numbers ranging from above 10 to 100,000. Here we demonstrated read classification results for all simulated species. E. avium classification results were consistent across all database instances. In addition, several other species were classified at >1000 reads with the normalized NCBI Nt database instances (Supplementary Data 3 and 4)

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