Fig. 4
From: Single-cell CAS-seq reveals a class of short PIWI-interacting RNAs in human oocytes
Potential function of oocyte short-PIWI-interacting RNAs (os-piRNAs). a Enrichment of human os-piRNAs in different gene elements compared to the random genomic distribution. b Proportion of intergenic os-piRNAs on the sense and antisense strand of different transposable elements (TEs) and their flanking regions. FL1k and FL2k represent the 0–1- and 1–2-kb flanking regions, respectively. c The proportion of os-piRNAs on the sense and antisense strand of transposons is classified according to their evolutionary origin. d The ratio of reads with both 1U and 10A in os-piRNAs derived from sense TEs is greater than those from antisense TEs or non-TE regions. e os-piRNAs derived from sense TEs contained more 10 nt pairs on the complementary strand. Average results in the six replicate samples of human oocytes are shown for a–e, and the error bars represent the standard deviation. f The density plot of the CpG and non-CpG methylation ratios of os-piRNA clusters, protein-coding genes, and non-coding genes. Source data of a–f are provided in the Source Data file
