Fig. 2
From: Target specific functions of EPL interneurons in olfactory circuits
TC/MC odor responses elevate without EPL-IN inhibition. a Experimental setup. b Representative TC/MC odor response. c Representative single cell odor response profile from TC or MC of control and EPL-IN Vgat knockout mice. d Average TC/MC odor response profiles of control and EPL-IN Vgat knockout animals. EPL Vgat KO: n = 51 cells across 11 mice, Control: n=55 cells across 12 mice, Odor 1*, Odor 36**, *p < 0.05, **p < 0.01, Bonferroni’s multiple comparisons test, p < 0.0001, 2-way ANOVA. e Normalized tuning curve comparing control vs EPL-IN Vgat knockout, p < 0.0001, 2-way ANOVA. f Absolute firing change during odor presentation comparing control vs EPL-IN Vgat knockout. Odor 1**, **p < 0.01, Bonferroni’s multiple comparisons test, p < 0.0001, 2-way ANOVA. g Z score analysis of odor response comparing EPL-IN Vgat knockout vs controls. Odor 1**, **p < 0.01, Bonferroni’s multiple comparisons test, p < 0.0001, 2-way ANOVA. h Baseline frequencies of all recorded neurons, Two-tailed t-test. i Absolute firing change of Off-Response comparing control vs EPL-IN Vgat knockout, Two-tailed t-test, Odor 1****, Odor 35**, Odor 36****p < 0.01, Bonferroni’s multiple comparisons test, p < 0.0001, 2-way ANOVA. j Z score analysis of Off-Response comparing EPL-IN Vgat knockout vs controls. Odor 1****, Odor 2**, **p < 0.01, ****p < 0.0001, Bonferroni’s multiple comparisons test, p < 0.0001, 2-way ANOVA. Averages ± SEM
