Fig. 1
From: LncRNA GLCC1 promotes colorectal carcinogenesis and glucose metabolism by stabilizing c-Myc
LncRNA candidate AF339830 is clinically relevant in colorectal cancer. a The flow chart for selected candidate lncRNAs in upregulated lncRNAs in colorectal cancer tissue and glycolysis-free cells is shown. b Statistical analysis of GLCC1 expression in 95 pairs of colorectal cancer and normal tissues, paired t-test. In boxplots (middle line depicts the median and the whiskers the min to max. range). c Survival was analyzed and compared between patients with low and high levels of GLCC1 in 95 patients with colorectal cancer (cohort 1), log-rank test. d ROC analysis of lncRNA GLCC1 in Renji cohort 1. e Comparing different tumor size and TNM stage between GLCC1 high-expression and GLCC1 low-expression tumors of Renji cohort 1. The heatmap illustrates the association of different clinical characters with GLCC1 high and low-expression tumors. Statistical significance was performed by the χ2 test. f Representative images of GLCC1 expression in colorectal cancer and adjacent colorectal tissues using ISH analysis in Renji cohort 2. The purple staining represents positive signal. Scale bar indicates 100 μm. g Survival was analyzed and compared between patients with high and low levels of GLCC1 expression in tumor in Renji cohort 2; n = 90, log-rank test
