Fig. 2
From: LncRNA GLCC1 promotes colorectal carcinogenesis and glucose metabolism by stabilizing c-Myc
GLCC1 is an oncogenic lncRNA in colorectal cancer. a–c Overview of GSEA used to identify the differential gene profiles between GLCC1 siRNA transfection colorectal cancer cells and controls. d, e Cell proliferation assay was performed in DLD-1 and HT29 cells transfected with GLCC1 siRNA1/2; n = 6. f Representative data of tumors in nude mice-bearing colorectal cancer cells transfected with PBS, control shRNA adenovirus, and GLCC1 shRNA adenovirus; n = 6. g Tumor volume was measured after GLCC1 shRNA adenovirus treatments in the xenograft mouse model; n = 6; p < 0.01. h Tumor weight was measured in mice after different treatments; n = 6. i, j Cell proliferation assay was performed in LoVo (i) and SW480 (j) cells transfected with GLCC1 overexpression plasmid; n = 3. Data in d, g, h–j are presented as the mean ± SE. p-values were calculated by one-way ANOVA followed by SNK multiple comparison test
