Fig. 1 | Nature Communications

Fig. 1

From: Challenging the point neuron dogma: FS basket cells as 2-stage nonlinear integrators

Fig. 1

Modeling tools used to study dendritic integration in FS BCs and its functional implications. a Detailed, biophysically constrained multi-compartmental models using realistic anatomical reconstructions. b Reduced two-stage integrate and fire models of FS BCs. c two-layer ANN reduction describing the FS BCs. d Reduced network model with simplified pyramidal, FS BCs and SOM + interneurons. FS BCs and SOM+ interneurons provide feedback inhibition to excitatory neurons, with FS BCs targeting the somatic subunit while SOM+ neurons target the dendritic subunits. Memory encoding afferents provide inputs to excitatory cell dendrites

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