Table 1 IC50 values of P1P5A against selected cell lines (μM)

From: Supramolecular trap for catching polyamines in cells as an anti-tumor strategy

Tumor types

Cell lines

IC50 (μM)

P1P5A

P2P5A

P3P5A

Breast cancer

MCF-7

18.40

92.06

58.69

Glioma

C6

30.16

>100

>100

U87

22.53

>100

73.43

Neuroma

Neuro-2a

8.52

79.75

45.07

Lung cancer

A549

34.81

>100

>100

Hepatocellular carcinoma

HepG-2

30.85

>100

>100

Normal

LO2

49.17

>100

>100

HUVEC

52.15

>100

>100