Fig. 1
Framework of the yeast GEM project. a Recording model updates in a community way using GitHub. b In Yeast8, genes, metabolites and reactions are annotated with their corresponding IDs from different databases, which simplifies translation between namespaces. Yeast8 forms the basis of the model ecosystem from which proYeast8DB, ecYeast8, etc., are derived. c Major steps of development from Yeast7 to Yeast8. d Subsystem statistical analysis for the reactions added to Yeast8. e Metabolomics mapping between Yeast7, Yeast8 and the YMDB database. f Comparison of Yeast7 and Yeast8 in percent accuracy of gene essentiality and substrate usage analysis, as well as in memote test total scores (divided by 100)
