Fig. 5
From: Interplay of protein corona and immune cells controls blood residency of liposomes
Leukocyte uptake of uncoated and pre-coated liposomes in whole blood. Cellular uptake of uncoated (empty triangles) and pre-coated (full triangles) liposomes in whole blood: DOTAP (red, panel a), DOPC (green, panel c), and DOPG (blue, panel e). The fluorescence of internalized liposomes was measured as the percentage of FITC positive cells by gating on distinct leukocyte subpopulations as indicated. The gating strategy was obtained as shown in Supplementary Fig. 3. Each value is the average of duplicate samples ± standard deviation within a single experiment. Statistical significance of difference in cellular uptake was evaluated using the Student’s t test: DOTAP (red, panel b), DOPC (green, panel d), and DOPG (blue, panel f). From top to bottom dashed lines indicate p-values: 0.05; 0.01; 0.005
