Fig. 3
From: Tumor exosome-based nanoparticles are efficient drug carriers for chemotherapy
Evaluation of exosomes sheathed on PSiNPs in E-PSiNPs. a Hydrodynamic diameter of PSiNPs and E-PSiNPs by DLS analysis. b TEM images of PSiNPs and E-PSiNPs. Scale bar: 200 nm. c Colocalization of DiO (green) and PSiNPs (red) in E-PSiNPs by confocal microscopy. Scale bar: 20 μm. d Colocalization of CD63 (green) and PSiNPs (red) in E-PSiNPs by confocal microscopy. Scale bar: 20 μm. e Immunoblotting analysis of exosome markers (TSG101 and CD63) and ER marker (calnexin) expressed in E-PSiNPs exocytosed from Bel7402 cells. f Yield of E-PSiNPs when Bel7402 cells were pretreated with 200 μg mL−1 PSiNPs for 6 h and then incubated in fresh medium containing 15 nM DMA or 10 μM ionomycin for 16 h by ICP-OES. Data were represented as mean ± SD (n = 3). **P < 0.01, ***P < 0.001 (one-way ANOVA with Fisher’s LSD test). Source data are provided as a Source Data file
