Table 1 The list of lung cancer samples used for initial cytologic quality check, 2D cell culture, organoid culture and PDX
From: Patient-derived lung cancer organoids as in vitro cancer models for therapeutic screening
Case | Patient sample | Sex | Age | Lung cancer type | Differentiation | Subtype | Cytologic quality check | 2D-culture | Organoid culture | PDX |
|---|---|---|---|---|---|---|---|---|---|---|
1 | LC-05 | F | 61 | Adenocarcinoma | Moderate | Papillary | Epithelial cell-like | + | + | − |
2 | LC-10 | F | 63 | Adenocarcinoma | Moderate | Papillary | Fibroblast-like | − | − | − |
3 | LC-13 | M | 75 | Squamous cell carcinoma | Moderate |  | Epithelial cell-like | + | + | − |
4 | LC-15 | F | 75 | Adenocarcinoma | Moderate | Papillary | Epithelial cell-like | + | + | − |
5 | LC-17 | M | 70 | Large cell carcinoma |  |  | Fibroblast-like | − | − | − |
6 | LC-18 | M | 59 | Adenocarcinoma |  | Foetal | Fibroblast-like | − | − | − |
7 | LC-21 | F | 74 | Small cell carcinoma |  |  | Epithelial cell-like | + | + | − |
8 | LC-22 | F | 55 | Adenocarcinoma | Poor | Micropapillary | Epithelial cell-like | + | + | − |
9 | LC-23 | M | 83 | Adenocarcinoma | Poor | Solid | No cell | − | − | − |
10 | LC-26 | F | 65 | Adenocarcinoma | Moderate | Papillary | Fibroblast-like | − | − | − |
11 | LC-28 | M | 78 | Squamous cell carcinoma | Moderate | Â | Epithelial cell-like | + | + | + |
12 | LC-29 | M | 57 | Large cell neuroendocrine carcinoma | Â | Â | Epithelial cell-like | + | + | + |
13 | LC-30 | M | 66 | Squamous cell carcinoma | Moderate | Â | Epithelial cell-like | + | + | + |
14 | LC-34 | F | 64 | Adenocarcinoma | Moderate | Acinar | Epithelial cell-like | + | + | + |
15 | LC-35 | F | 77 | Adenocarcinoma | Well | Mucinous | Fibroblast-like | − | − | − |
16 | LC-36 | M | 68 | Adenocarcinoma | Well | Lepidic | Epithelial cell-like | + | + | − |
17 | LC-37 | F | 54 | Adenocarcinoma | Moderate | Papillary | Fibroblast-like | − | − | − |
18 | LC-38 | M | 74 | Adenosquamous carcinoma |  |  | Epithelial cell-like | + | + | − |
19 | LC-39 | M | 75 | Adenocarcinoma | Poor | Solid | Fibroblast-like | − | − | − |
20 | LC-40 | M | 81 | Adenocarcinoma | Moderate | Acinar | No cell | − | − | − |
21 | LC-41 | M | 48 | Adenocarcinoma | Moderate | Papillary | Fibroblast-like | − | − | − |
22 | LC-42 | M | 82 | Squamous cell carcinoma | Moderate | Â | Epithelial cell-like | + | + | + |
23 | LC-43 | M | 71 | Adenocarcinoma | Poor | Solid | Epithelial cell-like | + | + | − |
24 | LC-46 | M | 71 | Combined small cell and large cell carcinoma |  |  | No cell | − | − | − |
25 | LC-47 | M | 72 | Squamous cell carcinoma | Moderate |  | No cell | − | − | − |
26 | LC-48 | F | 72 | Adenocarcinoma | Moderate | Papillary | No cell | − | − | − |
27 | LC-49 | M | 75 | Adenocarcinoma | Poor | Solid | Epithelial cell-like | + | + | + |
28 | LC-50 | M | 62 | Squamous cell carcinoma | Moderate | Â | Epithelial cell-like | + | + | + |
29 | LC-51 | M | 60 | Adenocarcinoma | Poor | Micropapillary | Epithelial cell-like | + | + | − |
30 | LC-52 | M | 72 | Squamous cell carcinoma | Moderate |  | Epithelial cell-like | + | + | − |
31 | LC-53 | M | 52 | Adenocarcinoma | Moderate | Acinar | Epithelial cell-like | + | − | − |
32 | LC-54 | M | 54 | Adenocarcinoma | Moderate | Papillary | Epithelial cell-like | + | − | − |
33 | LC-55 | M | 70 | Adenocarcinoma | Poor | Solid | Epithelial cell-like | + | + | + |
34 | LC-56 | M | 69 | Adenocarcinoma | Well | Mucinous | Epithelial cell-like | + | + | − |
35 | LC-57 | M | 69 | Squamous cell carcinoma | Well |  | Epithelial cell-like | + | − | + |
36 | LC-58 | M | 63 | Adenocarcinoma | Poor | Solid | Epithelial cell-like | + | + | + |
