Fig. 6 | Nature Communications

Fig. 6

From: Assisted reproductive technologies are associated with limited epigenetic variation at birth that largely resolves by adulthood

Fig. 6

No evidence for ART-associated DNA methylation change at repetitive elements. a Global DNA methylation was assessed by grouping EPIC probes into Alu or LINE1 repetitive element regions using the REMP tool. b Boxplot of mean DNA methylation level of all probes at Alu and LINE1 in neonatal and adult blood. An age-effect is observed, but no significant differences between control and ART groups are detected. Boxplot elements are: center line-median; box limits-upper (Q3) and lower (Q1) quartiles; whiskers–smallest and largest non-outlier; points-outliers. c. Mean DNA methylation across all 722,301 probes in neonatal and adult blood. d P-values based on mean Alu, LINE1 and all probe DNA methylation for each group, using a Student’s t-test

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