Fig. 4
Skin resistance modules and candidate genes associated with plasticity in ri. a The module negatively associated with ri. b The module positively associated with ri. These modules provided insight into the mechanisms underlying acclimation of ri by guiding subsequent analyses on gene ontology enrichment and hub gene identification. The figure also identifies four genes (CHRM3 (c), TRIM63 (d), ALOXE3 (e), and PDE4B (f)) within the skin resistance modules that correlated to plasticity in ri and were associated with GO terms related to water loss regulation. Temperature and humidity were not associated with the expression of these modules. Regressions are shown with 95% confidence intervals
