Fig. 1 | Nature Communications

Fig. 1

From: Heme and hemoglobin utilization by Mycobacterium tuberculosis

Fig. 1

Heme and hemoglobin utilization by M. tuberculosis and mutant strains. Growth of the avirulent Mtb strain mc26206 (wt; circles), the Δdpp mutant ML2436 (triangles), and the complemented Δdpp mutant (squares) in HdB minimal medium with a 10 µM ammonium ferric citrate and b 2.5 µM human hemoglobin (cyan) or 10 µM hemin (blue). Growth of Mtb mc26206 (circles), the Δppe36 mutant ML2411 (triangles) (c), and the Δppe62 mutant ML2412 (triangles) (d) in HdB minimal medium with 2.5 µM hemoglobin (cyan) or 10 µM hemin (blue). Medium with hemin and hemoglobin contained 20 µM of 2,2′-dipyridyl to prevent utilization of trace ferric iron. Error bars represent standard errors of mean values of biological triplicates. Source data are provided in the Source Data file

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