Fig. 3
From: Heme and hemoglobin utilization by Mycobacterium tuberculosis
The M. tuberculosis Δdpp mutant is resistant to heme toxicity and experiences iron starvation. a Growth of wt Mtb (circles), the Δdpp mutant (triangles), and the complemented Δdpp mutant (squares) in HdB minimal medium with 1 µM ammonium ferric citrate and increasing concentrations of hemin. Note that the scale of the y-axis is not linear. b The mRNA levels of mbt genes of wt Mtb, the Δdpp mutant, and the complemented Δdpp mutant in the presence of 10 µM hemin were determined by quantitative real-time PCR. Error bars represent standard errors of mean values of biological triplicates. For all plots, asterisks denote significant differences for Δdpp mutant compared to wt Mtb. Statistical significance was determined by Tukey’s HSD following an F-test (p < 0.05). Source data are provided in the Source Data file
