Fig. 1

Principle of retinal hyperspectral (HS) imaging. In HS imaging a narrow bandwidth tunable light source illuminates the retina and the reflected light from the retina is collected by an image sensor. The different frames of the hyperspectral reflectance cube are obtained by scanning the source wavelengths. Therefore, each HS image has both spatial and spectral information, i.e., each spatial locus has an associated spectrum when viewed across the available wavelengths. NIR = near-infra-red