Table 1 GSEA showing the top 25 pathways (Kyoto Encyclopedia of Genes) significantly enriched in proliferative and differentiated organoids^*

Ribosome

Lysosome

DNA replication

Endocytosis

Cell cycle

Focal adhesion

Parkinsons disease

Neuroactive ligand receptor interaction

Huntingtons disease

Regulation of actin cytoskeleton

Oxidative phosphorylation

Phosphatidylinositol signaling system

Spliceosome

Melanogenesis

Pyrimidine metabolism

Pathways in cancer

Alzheimers disease

Tight Junction

Purine metabolim

B cell receptor signaling

Base excision repair

Axon guidance

Mismatch repair

Inositol phosphate metabolism

Oocyte meiosis

Other glycan degradation

Nucleotide excision repair

Leukocyte transendothelial migration

Homologous recombination

Notch signaling pathway

RNA polymerase

Fcγ R-mediated phagocytosis

RNA degradation

Endometrial cancer

Systemic lupos erythematosus

Neurotrophin signaling pathway

Proteasome

Wnt signaling pathway

N-glycan biosynthesis

Mapk signaling pathway

Protein export

Apoptosis

Amino sugar and nucleotide sugar metabolism

Adherens Junction

Steroid biosynthesis

Acute myeloid leukemia

Progesterone-mediated oocyte maturation

Insuline signaling pathway

Cardiac muscle contraction

mTOR signaling pathway