Fig. 5
From: Surface-kinetics mediated mesoporous multipods for enhanced bacterial adhesion and inhibition
Surface topologies enhanced bacterial adhesion and inhibition. a SEM, b TEM images and (inset of a) 3D structural model of the tetra-pods Fe3O4@SiO2@RF&PMOs nanoparticles adhered on E. coli surfaces. Scale bars represent 1 μm for a, 100 nm for b. c Quantitative analyses of the nanoparticles adhered on bacteria from ICP based on Fe3+ concentration: the tetra-pods Fe3O4@SiO2@RF&PMOs (Tetra-pods), Janus Fe3O4@SiO2@RF&PMO (Janus) and core@shell Fe3O4@SiO2@RF&PMO (RF@PMO) nanocomposites. d Schematic illustration of the adhesion and magnetic induced separation of E. coli with the multipods nanocomposites. e Quantitative analysis of E. coli in the PBS solution after the magnetic induced separation process. Optical density (OD) value is positive correlated with the amount of bacteria in the solution. f E. coli inhibition efficiency of different nanoparticles loaded with the same amount of lysozyme within 24 h. g The time-dependent E. coli inhibition evaluation of different nanocomposites loaded with the same amount of lysozyme (400 μg mL−1). The bars represent mean ± s.d. derived from n = 3 groups of bacteria suspension. Source data underlying c, e–g are provided as a Source Data file. The statistical analysis was performed using one-way analysis of variance (ANOVA), followed by post hoc Tukey’s method. **P < 0.01
