Table 1 Reaction conditions optimizationa

From: Photoredox-catalyzed oxo-amination of aryl cyclopropanes

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Entry

Catalyst

Yield (%)

1

PC–I

64

2

PC–II

0

3

PC–III

68

4

PC–IV

65

5

PC–V

47

6

PC–VI

57

7

PC–III

74b

8

PC–III

85b, c

9

PC–III

85b, c, d

10

PC–III

0e

11

0

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  1. PC photoredox catalyst, DCE 1,2-dichloroethane
  2. aReactions were performed with 1a (0.1 mmol), 2a (0.3 mmol), photocatalyst (2 mol%) in 1,2-dichloroethane (0.5 mL), irradiating with 15 W blue LEDs under an air atmosphere at room temperature for 16 h. Yields were determined by 1H NMR using 1,1,2,2-tetrachloroethane as internal standard
  3. bUnder O2 atmosphere
  4. cWith 4 Å molecular sieves
  5. d0.2  mol% photoredox catalyst was used
  6. eEither without irradiation or under N2 atmosphere