Table 1 MR estimates for the effect of a 1 cm increase in height on partner’s height

From: Genetic evidence for assortative mating on alcohol consumption in the UK Biobank

Test

Interpretation

Estimate (95% C.I.)

P-value

Phenotypic association for comparison

N/A

0.24 (0.23, 0.25)

<10−16

Inverse-variance weighted

Primary causal estimatea

0.19 (0.18, 0.21)

<10−16

Heterogeneity of Inverse-variance weighted

Balanced pleiotropy

I2 = 3.6%

0.68

MR-Egger intercept

Intercept test for directional pleiotropyb

0.001 (−0.006, 0.008)

0.75

MR-Egger regression

Regression estimatea

0.19 (0.15, 0.21)

<10−16

Weighted median

Consistencya

0.18 (0.15, 0.21)

<10−16

Weighted mode

Consistencya

0.17 (−0.23, 0.57)

0.41

  1. aUnits: mm change in partner’s height per 1-unit increase in individual’s height
  2. bUnits: Average pleiotropic effect of a height genetic variant on partner’s height
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