Table 2 Meta-analysis of spousal-concordance for rs1229984 across centres

From: Genetic evidence for assortative mating on alcohol consumption in the UK Biobank

Recruitment centre

Number of spouse-pairs born within 100 km of each other

Beta (95% C.I.)

Stockport

9

N/Aa

Manchester

662

0.024 (−0.088, 0.0675)

Oxford

669

−0.010 (−0.088, 0.067)

Cardiff

930

0.022 (−0.043, 0.088)

Glasgow

1046

0.072 (0.019, 0.125)

Edinburgh

611

−0.047 (−0.166, 0.070)

Stoke

1215

−0.012 (−0.075, 0.051)

Reading

1352

0.003 (−0.055, 0.060)

Bury

2244

0.012 (−0.031, 0.055)

Newcastle

2976

−0.025 (−0.064, 0.013)

Leeds

2563

0.041 (0.001, 0.081)

Bristol

2117

0.015 (−0.030, 0.060)

St Bartholomew’s Hospital

122

−0.073 (−0.220, 0.074)

Nottingham

2342

0.025 (−0.017, 0.066)

Sheffield

2260

0.037 (−0.009, 0.082)

Liverpool

2632

0.023 (−0.020, 0.066)

Middlesbrough

1477

0.002 (−0.050, 0.053)

Hounslow

838

0.073 (−0.000, 0.147)

Croydon

1034

0.044 (−0.027, 0.115)

Birmingham

1440

−0.019 (−0.068, 0.031)

Swansea

85

−0.068 (−0.283, 0.146)

Wrexham

29

N/Aa

Combined (Fixed effects)

28,615

0.016 (0.004, 0.028) P = 0.011

  1. aLinear regression estimates did not converge due to limited sample sizes, these studies were excluded from the meta-analysis