Fig. 3 | Nature Communications

Fig. 3

From: First-in-human trial of blood–brain barrier opening in amyotrophic lateral sclerosis using MR-guided focused ultrasound

Fig. 3

Feasibility of blood–brain barrier opening using MRgFUS in the leg control region of the right primary motor cortex. a Leg control region mapping using motor-task functional MRI (fMRI). b, c show confirmation of successful blood–brain barrier permeabilization in the sonicated primary motor cortex area as demonstrated by new gadolinium enhancement in T1-weighted imaging. Subject one is represented in the top row and subject four in the bottom row

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