Fig. 4
From: Mouse embryo geometry drives formation of robust signaling gradients through receptor localization
BMP receptors localize at basolateral membrane of mouse epiblast in vivo. a Illustration of pre-gastrulation mouse embryo, showing transverse and sagittal sections. b Transverse section of an E6.25 mouse embryo stained for epiblast marker OCT4, BMPR1A, and ZO-1. c Plots of BMPR1A (left) and ZO-1 (right) staining intensity along apicobasal axis for transverse section from b show BMPR1A localized beneath tight junctions. d, e Same as in b, c but for a sagittal section of an E6.5 mouse embryo. These images are representative of two sets of images in two embryos/experiments. In mouse data, scale bar 20 µm. Error bars denote SEM
