Table 2 Subpopulation-specific GO terms enrichment results

From: DC3 is a method for deconvolution and coupled clustering from bulk and single-cell genomics data

-log10(p-value)

Original

Down-sampling

scRNA-seq

scRNA-seq + HiChIP

scRNA-seq

scRNA-seq + HiChIP

Subpop 1

neuron development

37.83

37.84

16.81

24.26

axon development

26.44

27.63

11.52

17.87

axonogenesis

18.12

20.12

10.01

16.55

neuron projection guidance

16.73

17.88

7.99

16.03

Subpop 2

cardiovascular system development

9.13

11.34

4.87

11.02

vasculature development

9.76

11.75

5.59

8.58

circulatory system development

7.17

9.93

3.89

8.87

muscle structure development

5.98

8.72

2.88

7.33

Subpop 3

forebrain development

11.32

13.26

1.44

13.03

central nervous system development

10.74

14.34

1.40

11.96

brain development

9.02

13.98

2.18

11.22

head development

8.77

12.05

1.57

9.51

  1. The enrichment p-values are transformed to −log10(p-values) and shown in the table. Original: scRNA-seq measured in SMART-seq with median ~1 million reads per cell; Down-sampling: simulated scRNA-seq measured in Drop-seq with median UMI ~5000
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