Fig. 4
From: Bacterial variability in the mammalian gut captured by a single-cell synthetic oscillator
The repressilator 2.0 is robust and informative within the mouse gut. a in vitro synchronized PAS715 (E. coli) bacteria measure growth in mice treated with a single dose of streptomycin (n = 3 per group). b Histograms of bacterial phase distributions throughout the experiment. Graphs show normalized counts. 5.75 h timepoint is compared to the gavage population (black line). Dotted lines represent datasets with angular deviation >1.2, which were excluded from downstream analyses. For number of colonies analyzed at each timepoint, see corresponding data in d. c Graph of average elapsed phase of the population vs time for each mouse. Graph shows mean with 95% CI. d Cumulative distribution functions of predicted generations elapsed since gavage. Source data are provided as a Source Data file
