Fig. 4
From: Synthetic protein-conductive membrane nanopores built with DNA
Transport of protein trypsin through DNA nanopore NP. a Scheme of the DNA nanopore and its interaction with protein molecules (green). b Single-channel current trace recorded at −50 mV in the presence of trypsin (66.7 µM) at the cis side leading to blockade. c Scatter plot showing dwell time τoff and amplitude A for single-channel current recordings with trypsin (66.7 μM) in the cis chamber. Points cluster into type I (light green) and type II (dark green) events. Each point in the diagram represents an individual encounter event of protein with the DNA nanopore. The scatter plot comprises 7282 data points from three independent DNA nanopore insertions. Electrical recordings were measured using the Orbit mini device which is grounded at the trans chamber. Source data are provided as a Source Data file
