Fig. 5
From: The TLR7/8 agonist R848 remodels tumor and host responses to promote survival in pancreatic cancer
Continuous R848 monotherapy extends survival in allografted PDAC. Experimental design (a), Kaplan-Meier curve comparing sham-treated, burst-treated R848, and continuous-treated R848 KxPxCx-engrafted mice compared by log rank test (b), food intake relative to sham controls (c), and body weight relative to initial measurement (d). n = 8/group. Values are depicted as mean ± SEM, unless fewer than three subjects were remaining in a group, for which individual values are plotted
